Note: Note you will already need to have the domain added to siteworx.
With the domain in siteworx you can add an apache include directly as the user.
The path that apache looks for files is below
/home/user/var/domain/apache/*.conf
So if the account was example and the domain was example.com we would probally want to create the file at /home/example/var/example.com/apache/proxy.conf.
Assuming the service listens on port 3000 the configuration would look like the following:
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ProxyPass / http://127.0.0.1:3000/
ProxyPassReverse / http://127.0.0.1:3000/