With the domain in siteworx you can add an apache include directly as the user.
The path that apache looks for files is below
/home/user/var/domain/apache/*.conf
So if the account was example and the domain was example.com we would probally want to create the file at /home/example/var/example.com/apache/proxy.conf
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Assuming the service listens on port 3000 the configuration would look like the following:
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ProxyPass / http://127.0.0.1:3000/
ProxyPassReverse / http://127.0.0.1:3000/